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* q for cardio 69
 #841680  
  notablebiochemist - 06/14/17 14:50
 
  hey could you clarify this?
FA says that CIN3 is carcinoma in situ and is IRREVERISBLE while pathoma says it is reverisble dysplasia and doesn't consider CIN3 as Carcinoma in situ, which one is correct?
 
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* Re:q for cardio 69
#3341124
  cardio69 - 06/16/17 04:09
 
  Hi,
Basically, when dysplastic pic involves the entire thickness of the epi you can called “PREinvasive neoplasm”/& carcinoma in situ. Once they cross the red line (BM) invade you simply called INVASIVE.
When mild dysplasia or 1/3 basal epi involve you tag it CIN I & when moderate dysplasia 2/3 of it involve you tag it CIN II and more than 2/3 that goes to server dysplasia CIN III and last not least if you see immature atypical cells that entire thickness of epi (1o 2 superficial layers what works for you) -> carcinoma in situ/CIN III.

For what u asking just know, MILD/I to MODERATE/II dysplasias below 2/3 may be completely reversible. And if I recall pathoma also mention CIN III rare reverse but again very rare and once reach CIS there is no point of return.
 
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* Re:q for cardio 69
#3341130
  notablebiochemist - 06/16/17 07:37
 
  thanks, btw do you plan to make a collection file for previous questions you've posted here?  
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* Re:q for cardio 69
#3341180
  cardio69 - 06/16/17 17:43
 
  Welcome.

You simply can go to the search box in the bottom of the page here & just type cardio69 & subject you study. I cover almost every subject integrated all steps on my Q/drills.
___________________________________________________________________________
Now ans following Qs;


What screen line for 32 y/o?
Can you grade the slide http://i.imgur.com/76PDjq8.png for me & tell me what type of cell you see @ "1 o’clock"?

 
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* Re:q for cardio 69
#3341235
  notablebiochemist - 06/17/17 11:13
 
  pap smear?
i'd say 2 and koilocyte, and btw koilocytes are characterized by enlargement of nucleus not shrinking right?
 
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* Re:q for cardio 69
#3341275
  cardio69 - 06/17/17 20:02
 
  If you look at thickness of epi you notice dysplastic & @ 9 o’clock you see the dysplastic, “Disordered cells” fill up 1/3 of that thickness of epi BM intact (& you are correct; those are koilocytotic change cell you notice @1). That make it *CIN I*
read my exp again, you remember I preach/2 "when moderate dysplasia 2/3 of it involve you tag it CIN II" or at least 1/2 which is not the case here.

Remember we start pap @21 y/o -> repeat every 3yrs -> [UNTIL 29] | after -> You do pap combo with HPV testing every 5 yrs.

Hope you clear by now.
 
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* Re:q for cardio 69
#3341287
  notablebiochemist - 06/18/17 04:24
 
  thank you very much  
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* Re:q for cardio 69
#3341355
  cardio69 - 06/18/17 20:40
 
  You're most welcome.  
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* Re:q for cardio 69
#3341435
  cardio69 - 06/19/17 15:51
 
  I post few Qs on the forum try them out.  
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