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* Q. Chlamydia and gonorrhoeae
 #837437  
  geniusone - 02/15/17 02:00
 
  We know they often occur together so we treat them together empirically with Ceftriaxone and azithromycin.

UW indicates that NAAT is highly sensitive 96% and highly specific 99%.

When NAAT confirms Chlamydia, we only treat Chlamydia with Azithromycin

BUT

When NAAT confirms gonorrhoeae, we treat BOTH with Ceftriaxone AND Azithromycin?


If NAAT is highly specific for both, why are we treating BOTH when NAAT confirms negative for Chlamydia and not treat both when NAAT confirms gonorrhoeae?



PS
I remember reading an article saying Azithromycin contributes in treating gonorrhoeae. Is that why?

 
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* Re:Q. Chlamydia and gonorrhoeae
#3328115
  jazpreet2000 - 02/15/17 09:14
 
  So we treat Chlamydia when NAAT says gonorrhea is present--because chalmydia is typically also discovered there (high chance). So notice here, NAAT was done for gonorrhea.

Chlamydia--number 1 STD in the USA. so when doing NAAT for chlamydia, don't need to treat for gonorrhea since its number 2 STD and isn't always found with chlamydia.

so chlamydia is found with gonorrhea but gonorrhea isn't always found with chlamydia--

i hope that helps!
 
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* Re:Q. Chlamydia and gonorrhoeae
#3328127
  7th_dance - 02/15/17 11:21
 
  When NAAT confirms gonorrhoeae, we treat BOTH with Ceftriaxone AND Azithromycin----

Azhitro is added NOT because you want to treat chlamydia(NAAT and very sensitive and Specific as you said), its added cuz ceftriaxone resistance is in increasing trend among the gonococcus, hence azithro added to kill the ceftriaxone resistant gonococci.

Adding azithro sometimes creates confusion as it is used to treat chlamydia. But adding this for NAAT positive Gonococci is for complete treatment, not for coexisting chlamydia.
 
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* Re:Q. Chlamydia and gonorrhoeae
#3328128
  jazpreet2000 - 02/15/17 11:24
 
  ty!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!  
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* Re:Q. Chlamydia and gonorrhoeae
#3328213
  geniusone - 02/15/17 21:17
 
  ty 7th dance, that makes sense :)  
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