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  yousmle99 - 02/13/18 15:35
 
  Why is it difficult to obtain a live, attenuated influenza virus vaccine?

(A) Antigen drifting results from major point mutations in the matrix protein
(B) The host immune response is poor
(C) Antigen shifts involving changes in hemagglutinin (H), neuramindase (N), or both occur
(D) It is not possible to serotype the viruses properly
(E) It is not possible to isolate the virus
 
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