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nbme 1 blk 1 q 43 and 44 - mtor
#1
hi can any one explain 43 44 q in nbme 1 blk 1 thnk u
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#2
43. first step: which artery is involved? as seen in angiogram this artery arise form proximal portion of basilar artery, so this is anterior inferior cerebellar artery (AICA).
secont step: which structures supply AICA. AICA supplies the caudal lateral pontine tegmentum, and inferior surface of the cerebellum.
third step: choose from given answer options which is characteristic for cerebellar dysfunction. a, d, e are characteristic for hemesphere
c. is characteristic for basal ganglia
only b. ataxic limb movements left. which is the correct answer.

44. - delta G means that reaction is favourabe. More - delta G, more favourable reaction. +delta means that reaction is unfavourable. More + delta G, more unfavourable the reaction.
So V->W reaction (deltaG -4,0) very favourable, it will lead to accumulation of large quantitie of product W.
In the presence of large amount of W, second little unfavourable reaction (deltaG +0,4)
W->X will proceed.
X->Z reaction (deltaG -3,5) is also very favourable, and results in accumulation of product Y.
last reaction (deltaG +5,7) very unfavourable. so it would not occur at all.
So correct answer is D. Y will accumulate in the largest amount at equilibrium.

Hope this helps.
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#3
goforward thnk u soooooooo much this delta g ,u r excellent.no words.just rock forward u will be in forward of all.all the best
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#4
Thank you.
Good luck.
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#5
thank u very much..............goforward
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#6
You are welcome. GL.
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