03-06-2011, 12:03 AM
please choose and answer the Qs in order from 11 to 20 with a brief explanation.
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NBME#1 block 1 Q11-----------Q20 - maryam2009
NBME#1 block 1 Q11-----------Q20 - maryam2009
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NBME#1 block 1 Q11-----------Q20 - maryam2009
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03-06-2011, 12:48 AM
Q11.D
renaturation under stringent conditions (e.g., shift from 100 degrees C to temperature about 25 degrees C below the Tm) can result in perfect base-pairing of homogeneous DNA (i.e., reconstitution of original double-stranded DNA). Note: Mismatched sequences can be distinguished from perfectly matched sequences.The melting temperature is reduced 1 degree C for every 1% mismatch (for example, 1 mismatch out of a sequence of 25 is 4% mismatch and a 4 degree C drop in melting temperature). renaturation under stringent conditions using radioactively labeled nucleic acid probes allows detection of specific DNA and RNA molecules (Southern blot and Northern blot techniques respectively
03-06-2011, 04:19 PM
Q 14
diphenhydramine = antihistaminic Toxicity---> decreased motility--> constipation(antimuscarinic effect)
03-06-2011, 07:07 PM
Q 16
intracranial calcifications in patients with AIDS--> Toxaplasma
03-06-2011, 07:21 PM
Q 19
Orthostatic intolerance. Treatment of choice for increasing blood volume is Fludrocortisone --> low K serum, high K excretion http://en.wikipedia.org/wiki/Orthostatic_intolerance http://en.wikipedia.org/wiki/Fludrocortisone
03-06-2011, 07:28 PM
choice A or C? I think the Renin should be increased A but the answer is C,why?
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