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Molecular biology 1...Q - maryam2009
#1
A researcher has designed a study in which she will compare the variability of alleles for two hundred genes on four chromosomes between two populations: two thousand children with low-functioning autism and two thousand children with no developmental or other disorder. Which tool will be the most useful for identifying allele variability?

A.Allele-specific oligonucleotide probes
B.DNA hybridization chips
C.Small interfering RNA
D.Restriction fragment length polymorphisms
E.Variable number tandem repeats
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#2
D
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#3
dd
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#4
AA ?
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#5
EE???

Explain the answer plz....
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#6
The correct answer is D.

Restriction fragment length polymorphisms.RFLP's are useful when a researcher is looking for genetic variabilty

Allele-specific oligonucleotide probes (A) is used to identify a particular mutation,, or to count chromosomes.

B is used to identify a set of single nucleotide polymorphisms.it’s most commonly used to measure gene expression in certain cells or tissues.

siRNAs © would be used to modulate gene expression at the transcriptional/post-transcriptional level.

VNTRs (E) are used for DNA fingerprinting
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#7
?? allele specific oligonucleotide probe
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#8
thanks for the great question and explanation
Your exam must be near
Best of luck
God bless you
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#9
You are welcome

Still working Smile
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