10-30-2006, 10:28 PM
A 39-year-old female has fingers that are tapered and
clawlike, with decreased motion at the small joints. The
microscopic appearance of the skin is shown in the figure.
She also has diffuse interstitial fibrosis of the lungs, with
pulmonary hypertension and cot pulmonale. Which of the
following dermal inflammatory cells is considered the most
likely initiator of the process that results in her skin dis-
ease?
O (A) CD4 lymphocyte
O (B) Macrophage
O © Mast cell
O (D) Neutrophil
O (E) NK cell
clawlike, with decreased motion at the small joints. The
microscopic appearance of the skin is shown in the figure.
She also has diffuse interstitial fibrosis of the lungs, with
pulmonary hypertension and cot pulmonale. Which of the
following dermal inflammatory cells is considered the most
likely initiator of the process that results in her skin dis-
ease?
O (A) CD4 lymphocyte
O (B) Macrophage
O © Mast cell
O (D) Neutrophil
O (E) NK cell