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If a patient with dyspnea, chest pain and abnormal radiography undergoes V/Q scanning, which statement is true in terms of the diagnosis of pulmonary embolism?

A. Matched defects make the diagnosis uncertain.
B. Unmatched defects rule out the diagnosis.
C. Pulmonary arteriography is indicated if clinical suspicion is low.
D. Matched defects make the diagnosis virtually certain.

Matched defects make the diagnosis uncertain