03-25-2007, 04:34 PM
4 drugs produce 4 therapeutic effect by the same mechanism.but each has unique toxicity.When used in maximal effective therapeutic dose,the drugs with which of the following characteristics is most likely to have highest incidence of toxicity?
Median eff. dose, Toxic dose(1)/effective dose(99)
A 0.5x, 2.8
B 1x, 2.1
C 5x, 2.4
D 33x, 3
Plz dont forget to explain ur answer.
Median eff. dose, Toxic dose(1)/effective dose(99)
A 0.5x, 2.8
B 1x, 2.1
C 5x, 2.4
D 33x, 3
Plz dont forget to explain ur answer.