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DNA from Escherichia coli and Haemophilus influenzae is digested with the restriction endonuclease EcoRI and the fragments separated by agarose gel electrophoresis. An examination of the gel shows that the DNA from H. influenzae was cleaved into numerous smaller fragments while that from E. coli was not. Which of the following best explains this difference?

A. Methylation of E. coli DNA
B. Methylation of H. influenzae DNA
C. Presence of introns in E. coli DNA
D. Presence of introns in H. influenzae DNA
E. Presence of transposons in E. coli DNA
F. Presence of transposons in H. influenzae DNA

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A. Methylation of E. coli DNA