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THIS QUESTION IS SO EASY BUT I HAVE A DOUBT IN IT
WHY ARE THEY TALKING ABOUT RECURRENT SINUSISTIS AND PNEUMONIA
please explain

a 3 year old male experiences recurrent sinusitis and one episode of pneumonia
as a partof his eveluation CANDIDA extracts is injected intradermally
48 hrs later he returns with a firm nodule measuring 16 mm in diameter in location where the extract was injected
which of the cell types are responsible for the response observed?
1.T CELL
2.B CELL

t cell

WHY THE HELL ARE THEY TALKING ABOPUT RECURRENT SINUSISTIS AND PNEUMONIA?

wiskott-aldrich syndrome, t cell def, recurrent infections, low polysacharide defense

or aggammaglobulinemia of bruton? what do you think

its a UW Q and they have simply called it a TYPE IV hypersensitivity reaction(delayed)
thats y i am confused with the questions

Recurrant infection is the key to the Diagnosis.The Question tells you its a Candida infection and is recurrant...
The nodules they are talking about are the caseating granulomas,,Bacteria and Systemic fungi are known bugs to cause caseating granulomas and the mechanism behind it is Type IV Delayed Hypersensitivity.

goljan says: any granoluma reaction (like PPD+), is type 4....and the questions asks:which of the cell types are responsible for the response observed?
all the other stuffs are crap.....distractions...

Agree, confused Q. If he is T cell deficient, like AIDS pt, type 4 hyperreaction is low and his PPD is neg.