01-21-2008, 02:43 PM
A 38-year-old business man develops severe diarrhea after returning from a business trip in Thailand. His stools are bloody, and he has been having fevers to 40 C (104 F). A stool culture grows gram-negative, non-motile organisms that do not ferment lactose. The toxin produced by the causative organism has which of the following molecular effects?
A. Inhibition of acetylcholine release
B. Disruption of rRNA interaction with EF-1 and EF-2
C. Activation of Gs
D. Inactivation of Gi
E. ADP ribosylation of EF-2
A. Inhibition of acetylcholine release
B. Disruption of rRNA interaction with EF-1 and EF-2
C. Activation of Gs
D. Inactivation of Gi
E. ADP ribosylation of EF-2