06-14-2008, 03:27 AM
a respiratory stable pateint with diagnosis of GBS, will u treat him with plasmapherisis first or give him immunoglobulin prior to plasmaphersis?
comments ??
comments ??
06-14-2008, 03:27 AM
06-14-2008, 03:28 AM
both are of equal and doubtful efficacy fo Ig BETTER??
06-14-2008, 03:32 AM
Only plasma exchange (PE) therapy and intravenous immune serum globulin (IVIG) have proven effective. Both therapies have been shown to shorten recovery time by as much as 50%. IVIG is easier to administer and has fewer complications than plasma exchange.25 The cost and efficacy of the 2 treatments are comparable.
Randomized trials in severe disease show that IVIG started within 4 weeks from onset hastens recovery as much as plasma exchange.26, 27, 28, 29 Combining plasma exchange and IVIG neither improved outcomes nor shortened the duration of illness.30 IVIG has also been proven safe and effective in the treatment of pediatric GBS.30, 31 Additionally, IVIG is the preferential treatment in hemodynamically unstable patients and in those unable to ambulate independently
emedicine
Randomized trials in severe disease show that IVIG started within 4 weeks from onset hastens recovery as much as plasma exchange.26, 27, 28, 29 Combining plasma exchange and IVIG neither improved outcomes nor shortened the duration of illness.30 IVIG has also been proven safe and effective in the treatment of pediatric GBS.30, 31 Additionally, IVIG is the preferential treatment in hemodynamically unstable patients and in those unable to ambulate independently
emedicine
06-14-2008, 06:30 AM
immediately treat with Ig+ plasma exchange.
I read som where it has to be done with in 2 hr of diagnosis???
I read som where it has to be done with in 2 hr of diagnosis???