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. Beta-Thalassemia results in the reduction of beta chains of hemoglobin due to errors in the processing of the initial mRNA transcript. The mechanism is most likely to involve a single nucleotide change in which of the following?

A. AUG start codon
B. Enhancer element in the first intron
C. Splice site
D. Termination codon
E. Upstream promoter element

c

explain

Reduction of beta chains in the haemoglobin result on mutation of a protein through splice sites and splicing of beta globin mRNA are responsible for few cases of beta thalassemia....