08-09-2009, 11:56 AM
08-09-2009, 12:03 PM
Pernicious anemia is identified with a high MCV and a normal MCHC (that is, it is a macrocytic, normochromic anemia). [9]. Ovalocytes are also typically seen on the blood smear, and a pathognomonic feature of megaloblastic anemias (which include pernicious anemia and others) is hypersegmented neutrophils.
08-09-2009, 12:04 PM
Approximately 90% of individuals with pernicious anemia have antibodies for parietal cells; however only 50% of all individuals in the general population with these antibodies have pernicious anemia.
08-09-2009, 12:08 PM
so Abs for intrinsic factor, final answer?
08-09-2009, 12:15 PM
schilling test is obsolete so 4 exam purpose intrinsic factor ab
08-09-2009, 01:02 PM
initial test- - Look for the choice if there is---
cbc with pbf
/serum B12 level
/methylmalonic acid level
if ccs i would like to advice first two (even i think no harm to advice for above three)
definitive test: anti-parietal cell and anti-intrinsic factor antibody
cbc with pbf
/serum B12 level
/methylmalonic acid level
if ccs i would like to advice first two (even i think no harm to advice for above three)
definitive test: anti-parietal cell and anti-intrinsic factor antibody