Which one of the following medications should be discontinued in a patient with diabetic
gastroparesis?
A) Exenatide (Byetta)
B) Benazepril (Lotensin)
C) Metformin (Glucophage)
D) Hydrochlorothiazide
E) Prochlorperazine maleate
E) Prochlorperazine maleate due to anticholinergic property
A-Byetta
Delayed gastric emptying may be caused or exacerbated by medications for diabetes, including amylin analogues (e.g., pramlintide) and glucagon-like peptide 1 (e.g., exenatide). Delayed gastric emptying has a direct effect on glucose metabolism, in addition to being a means of reducing the severity of postprandial hyperglycemia. In a clinical trial of exenatide, nausea occurred in 57% of patients and vomiting occurred in 19%, which led to the cessation of treatment in about one-third of patients. The other medications listed
do not cause delayed gastric emptying.
thanks...just know that byetta can cause pancreatitis?