09-11-2009, 01:21 PM
A 12-month-old boy is brought to the office by his mother for his routine health check-up. She informs you that she has just
been diagnosed with hypercholesterolemia. Her fasting serum total cholesterol concentration was 260 mg/dL and her
LDL-cholesterol concentration was 130 mg/dL (rec less than 129 mg/dL). She is unaware of a family history of coronary artery
disease because she was raised by her godmother when her parents died in their early 30s in a motor vehicle accident. A
special diet has been recommended for her; however, she is very concerned about the risk of hypercholesterolemia for her
son. The most appropriate management at this time is to
(A) ask her to reduce the child's fat intake and give him skim milk instead of whole milk
(B) do nothing until the child is 2 years of age
© have the child return for a fasting lipoprotein analysis
(D) obtain a random serum total cholesterol concentration for the child today
(E) refer the child to a lipid specialist
During a routine physical examination of a 2-week-old Jewish neonate, a grade 3/6 early systolic murmur is heard. The
mother reports no signs or symptoms of illness in the baby. The neonate is otherwise asymptomatic. Physical examination at
birth was normal. The most appropriate next step is to
(A) do funduscopic examination
(B) measure arterial blood pressures in the arms and legs
© order abdominal ultrasonography
(D) order chest x-ray film
(E) order electrocardiography
A 29-year-old Italian-American woman comes to the office for her first prenatal visit. Her last menstrual period was
16 weeks ago. This is her first pregnancy; her family history is unremarkable. She has heard that people ofMediterranean
ancestry are at risk for carrying a gene for β-thalassemia. She asks to be tested for this. Which of the following is the most
appropriate initial diagnostic study?
(A) Complete blood count with red cell indices
(B) Hemoglobin electrophoresis
© Red cell osmotic fragility test
(D) Restriction-fragment length polymorphism (RFLP) analysis of her β-globin gene
(E) Reticulocyte count
been diagnosed with hypercholesterolemia. Her fasting serum total cholesterol concentration was 260 mg/dL and her
LDL-cholesterol concentration was 130 mg/dL (rec less than 129 mg/dL). She is unaware of a family history of coronary artery
disease because she was raised by her godmother when her parents died in their early 30s in a motor vehicle accident. A
special diet has been recommended for her; however, she is very concerned about the risk of hypercholesterolemia for her
son. The most appropriate management at this time is to
(A) ask her to reduce the child's fat intake and give him skim milk instead of whole milk
(B) do nothing until the child is 2 years of age
© have the child return for a fasting lipoprotein analysis
(D) obtain a random serum total cholesterol concentration for the child today
(E) refer the child to a lipid specialist
During a routine physical examination of a 2-week-old Jewish neonate, a grade 3/6 early systolic murmur is heard. The
mother reports no signs or symptoms of illness in the baby. The neonate is otherwise asymptomatic. Physical examination at
birth was normal. The most appropriate next step is to
(A) do funduscopic examination
(B) measure arterial blood pressures in the arms and legs
© order abdominal ultrasonography
(D) order chest x-ray film
(E) order electrocardiography
A 29-year-old Italian-American woman comes to the office for her first prenatal visit. Her last menstrual period was
16 weeks ago. This is her first pregnancy; her family history is unremarkable. She has heard that people ofMediterranean
ancestry are at risk for carrying a gene for β-thalassemia. She asks to be tested for this. Which of the following is the most
appropriate initial diagnostic study?
(A) Complete blood count with red cell indices
(B) Hemoglobin electrophoresis
© Red cell osmotic fragility test
(D) Restriction-fragment length polymorphism (RFLP) analysis of her β-globin gene
(E) Reticulocyte count