05-11-2010, 07:07 PM
Mistargeting of lysosomal enzymes, a problem identified in patients with mucolipidosis II (I-cell disease), involves a defect in which of the following mechanisms involving lysosomal proteins?
A. N-linked glycosylation
B. O-linked glycosylation
C. Phosphorylation of mannose residues
D. Protease responsible for conversion of precursor
E. Sialylation of N-linked oligosaccharides
A. N-linked glycosylation
B. O-linked glycosylation
C. Phosphorylation of mannose residues
D. Protease responsible for conversion of precursor
E. Sialylation of N-linked oligosaccharides