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 A 49-year-old blue-eyed, blonde-haired Caucasian woman presents to clinic requesting treatment for "this unattractive redness of my facial skin." She reports that in the past three months, she has developed new blemishes on her nose, cheeks, and chin. She has also noticed that she now flushes intensely in response to extreme temperatures, emotion, and the consumption of spicy foods or alcohol. Based on recommendations from her friends, she modified her diet and tried various herbal preparations and skin creams, but nothing has alleviated her symptoms. She has no history of dermatological problems and did not have acne as a teenager. She has already undergone menopause.n Physical examination reveals a reddening of the central face, erythematous papules on the chin, and multiple telangiectasias on the nose and cheeks. Her skin is very fair otherwise.
Which of the following is the most appropriate treatment of this condition?

Options
1. Oral griseofulvin
2. Topical clindamycin
3. Topical isotretinoin
4. Topical metronidazole
5. Topical permethrin

4. rosacea