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It has been suggested that schizophrenia is more severe and has an earlier age of onset in the more recent generations of schizophrenia families. If so, this would be an example of which one of the following?

A. The two-hit model
B. Imprinting
C. Delayed age of onset
D. Anticipation
E. Increased numbers of mutagens in more recent generations

DDDDDDDDDDDDDDDDD

Aaa

Gusmle )).....That's the spirit )

will post answers in a little bit........

D. Anticipation

Answer is D.

More severe disease with an earlier age of onset in succeeding generations is called anticipation.
It can also be observed in diseases with triplet repeat expansions, such as Fragile X syndrome.

@Moka: I also selected choice A at first