12-20-2011, 09:50 AM
DKC(Dyskeratosis congenital) is a genetically inherited disease....proliferate capacity of stem cells is markedly impaired.The defect has been traced to inadequate production of an ezyme needed for Chromosome duplication in the nuclei of rapidly dividing cells.
Structural analysis shows the active site of this protein contains a SS-RNA that is required for normal catalytic function.Which step in DNA replication is most likely deficient in DKC patients?
A.syntesis of Centromeres
B.synthesis of Okasaki fragments
C.synthesis of RNA primers
D.Synthesis of telomeres
D.Removal of RNA primers
Please explain your answer . Thank you.
Structural analysis shows the active site of this protein contains a SS-RNA that is required for normal catalytic function.Which step in DNA replication is most likely deficient in DKC patients?
A.syntesis of Centromeres
B.synthesis of Okasaki fragments
C.synthesis of RNA primers
D.Synthesis of telomeres
D.Removal of RNA primers
Please explain your answer . Thank you.