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A 24 year old woman with a history of allergic rhinitis is involved in a automobile accident and sustains a splenic laceration. She undergoes abdominal surgery and is then transfused with 4 units of blood with the appropriate ABO and Rh type. as the transfusion progresses she becomes rapidly hypotensive and develop airway edema consistent with anaphylaxis. Which of the preexistent conditions best accounts for this symptoms?
A.AIDS
B. Cl esterase inhibitor deficiency
C. DiGeorge syndrome
D. selective IgA deficiency
E. Wiskott-Aldrich syndrome

D. selective IgA deficiency

it is selective IgA deficiency

good job both of u.. In IgA deficiency, anaphylaxis may occur if patient is exposed to blood products containing IgA (Goljan p33)