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5. A 67-year-old man comes to the office for an initial visit. He says his daughter, who is a patient in your practice, "made me come" because of a lesion in his mouth under his tongue. He is a farmer from the South who is visiting his daughter, and he is not concerned about the lesion. He says, "It has been present for a couple of months, and although I can feel it with the tip of my tongue and it is slightly sore, it doesn't give me any trouble." He has always been healthy and takes no medication. He drinks alcohol in small amounts on weekends, and he uses tobacco in a variety of forms. On physical examination, a 2H2-cm, raised, roughened gray lesion on the oral mucosa of the left side of the floor of the mouth is noted extending to the base of the tongue. You decide the lesion is highly suggestive of a malignancy and that a biopsy should be obtained. Based on the patient's history and incidence of lesions in this location, the lesion is most likely which of the following?

A) Adenocarcinoma
B) Basal cell carcinoma
C) Leukoplakia
D) Lymphoma
E) Squamous cell carcinoma

C or E ? Please explain.............

B...

Floor of mouth lesions

anyone else...

E. basal cell is upper lip and up. SCC is most common in this location and also the history of alcohol and tobacco - all favor SCC

i will say EE ......squamous cell carcinoma .


strong risk factor is in history ( smoking and alcohol )
most of the time is in mucosal surface ( mouth )
small and hard



leukoplakia : white in color , chornic irritation
develope SCC 2-6%
alcohol/smoking is risk factor
can not removed easily
laterl border of tongue ( location )

Thanks clinical and peace4all for the explaination

E. Risk factor of smoking and alcohol

Most probable E, pt 's taking tobacco in variety of forms -esp chewing cigars predisposes to it.

Can u people exclude LEUKOPLAKIA ??

@carnation 10, plz send me offline nbme at vatsalshruti
thanks a million..