USMLE Forum - Largest USMLE Community

An investigator is studying bacterial virulence factors. Ferric uptake regulation protein (Fur) binds tightly to DNA a short distance from the 5’end of the genes for these virulence factors. The concentrations of the virulence factors of the bacteria are observed under low-iron and high-iron conditions. Results show that the efficacy of Fur binding increases as the concentration of iron in the culture media increases. Based on these findings, Fur most likely regulates which of the following processes in these bacteria?

a. Methylation
b. Post-transcriptional modification
c. Splicing
d. Transcription
e. Translation

I think it's "e"
Since they r talking about the protein n it's binding upstream to 5'mrna. Probably saying this , it refers to the transcription initiation site .

It's not E. I got it wrong.

FUR “superfamily”; versatility & diversity of KEY transcriptional/D* referee

From Brazil
Congrats to Brazil gold medal WELL DONE gooooo https://www.youtube.com/watch?v=5FX-SHdznt4
Enjoy..

A?

it D.they are talking about enhancer and Trancription Factor .in the process of transcription

D. Transcription

- Fur is a TRANSCRIPTION FACTOR that acts as a REPRESSOR to control the gene expression.

- if INCREASE IRON CONCENTRATION--> INCREASE Fur DNA binding = INCREASE the REPRESSOR function and the opposite action w/ [LOW IRON].

- Fur helps in the BACTERIAL VIRULENCE FACTORS control.

HOPE THIS CAN HELP EVERYONE WITH THE SAME DOUBT
HERE IS A LINK W MORE INFO: https://en.wikipedia.org/wiki/Ferric_upt...tor_family