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A patient presents to an ophthalmologist complaining of difficulty reading in the afternoons and evenings because his eyelids get "too heavy" and he gets double vision. The ophthalmologist is concerned about a paraneoplastic syndrome because the patient also has a recent unexplained 20 lb weight loss. Which of the following tumors would be most likely to produce this patient's symptoms?

A. Breast carcinoma or renal cell carcinoma

B. Bronchogenic carcinoma or intracranial neoplasm

C. Lymphoma or myeloma

D. Renal cell carcinoma or parathyroid adenoma

E. Thymoma or bronchogenic carcinoma

E....lambert eaton

is this lambert-eaton syn???
B???

B? not sure

E...

hey.. paraneoplastic cerebellar degeneration ---> dizziness, double vision.
tumors most frequently involved are SCLC , ca breast and ovary and Hodgkins lymphoma.
patients with SCLC can also develop LE syn.
ans is E

so whats ans docM?

The correct answer is E.

The patient is suffering from myasthenia gravis, which is caused by an autoimmune attack on the nicotinic acetylcholine receptor of the skeletal muscle motor end plate.

Symptoms include early muscle fatigue, often beginning with the small, active muscles around the eyes.

Myasthenia gravis can be associated with thymoma and bronchogenic carcinoma.