USMLE Forum - Largest USMLE Community
Let's get this done! - mutation - Printable Version

+- USMLE Forum - Largest USMLE Community (https://www.usmleforum.com)
+-- Forum: USMLE Forum (https://www.usmleforum.com/forumdisplay.php?fid=1)
+--- Forum: Step 1 (https://www.usmleforum.com/forumdisplay.php?fid=2)
+--- Thread: Let's get this done! - mutation (/showthread.php?tid=668137)



0 - ArchivalUser - 04-01-2012

That took longer than expected, but finished the video. Going to take a quick 5 minute break and then review resp.


0 - ArchivalUser - 04-01-2012

hey guys do u know how to remember the onco genes and supressor genes ,, some common ones are ok .. but i seem to mess it up most of the time?


0 - ArchivalUser - 04-01-2012

I only know of this one:

Tumor suppressor vs. proto-onogene mutations: recessive vs. dominant
Recess Suppress: Tumor suppressor mutations are recessive. Proto-oncogenes are opposite (dominant).

Aside from that for specific oncogenes/suppressor genes, I don't know of any but I'll let you know if I come across any.



---
N-acetylcysteine used in:
(1) acetaminophen OD
(2) mucolytic (in CF pt)
(3) prevent radiocontrast nephropathy


0 - ArchivalUser - 04-01-2012

mutation .. thanks dear ,, thats kinda confusing for me ,, but i ll push it ion my brain.. my brain looks like a big can with lots of holes in it .. more u put more it leaks out!

ok here s q for u

whats mech of NAC here ?


0 - ArchivalUser - 04-01-2012

9:15 pm, done with one block review of UW, will take 1 hour break.

Welcome mutation, thank you for your inputs as wellSmile

@ owlcity about oncogenes doing questions work for me, and FA is great also. Try to make connections, mneumonics whatever works for you, and also repetition.


0 - ArchivalUser - 04-01-2012

N-acetylcysteine cleaves disulfide bonds that are in the mucus glycoproteins --> reduces viscosity.

Not to worry, Owl! Seems like brains are getting saturated, BUT we just need to figure out ways to stimulate the transcription factor to synthesize more receptors to be able to take in more information. See what I did there, haha.

I am definitely tired!


0 - ArchivalUser - 04-01-2012

@mutation

addition
NAC also acts a glutathione substitute and binds to toxic metabolites ,,
it also provides a sulphhydril grp to enhance the non toxic sulfation elimination of acetaminophen
( as per my notes)

done with gen path .. will start cvs tom ..

gn guys ,, its ovr for me here ..


0 - ArchivalUser - 04-01-2012

Time for pathoma! I am going to be doing female repro.


0 - ArchivalUser - 04-01-2012

Awesome, thanks, Owl! Good night!


0 - ArchivalUser - 04-01-2012

10:45 I am back late, time just flies by when you dont study Wink Will do one more UW block review. Thank you for the notes everybody.