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+--- Thread: hematology8 - kashmala (/showthread.php?tid=108741)
hematology8 - kashmala - ArchivalUser - 08-10-2006
A 40-year-old woman has had a week long course of fever and mental confusion. Physical examination shows T 38.2 C, P 100/minute, RR 20/minute, and BP 100/60 mm Hg. She has widespread petechiae of skin and mucosal surfaces. Laboratory studies show her serum urea nitrogen is 52 mg/dL with creatinine 5.3 mg/dL. She has a hemoglobin of 12.2 g/dL, hematocrit 36.8%, MCV 93 fL, platelet count 19,000/microliter, and WBC count 8180/microliter. Schistocytes are seen on her peripheral blood smear. Her condition deteriorates rapidly following platelet transfusion. At autopsy, pink hyaline thrombi are found in small myocardial arteries. Which of the following is the most likely diagnosis?
A Disseminated intravascular coagulopathy
B Idiopathic thrombocytopenic purpura
C Thrombotic thrombocytopenic purpura
D Trousseau syndrome
E Warm autoimmune hemolytic anemia
0 - ArchivalUser - 08-10-2006
a..
0 - ArchivalUser - 08-10-2006
E........
0 - ArchivalUser - 08-10-2006
TTP characteristic pentad of fever, renal failure, thrombocytopenia, hemolytic anemia, neurologic symptoms...
0 - ArchivalUser - 08-10-2006
a...........
0 - ArchivalUser - 08-10-2006
c....
situtation deteriotates after plt transfusion.... i think that differentiates
0 - ArchivalUser - 08-10-2006
WELL i was thinking of Septi shock with Schistocytes are seen on her peripheral blood smear
i pcked DIC but could be TTP
0 - ArchivalUser - 08-10-2006
answr is TTP.
0 - ArchivalUser - 08-10-2006
TTP.........