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+--- Thread: 14 yr old boy - zarah (/showthread.php?tid=111901)
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14 yr old boy - zarah - ArchivalUser - 08-24-2006
A 14-year-old male is seen by his pediatrician because he has recently been having problems with walking - he is becoming clumsy and having difficulties climbing. Upon examination, the physician notes that his calf muscles are hypertrophic. A DNA test is ordered, and a deletion is found in a gene on the X chromosome. What is the most probable diagnosis for this child?
A Becker muscular dystrophy
B Duchenne muscular dystrophy
C Limb-girdle muscular dystrophy
D Myasthenia gravis
E Spinal muscular atrophy
0 - ArchivalUser - 08-24-2006
b.
0 - ArchivalUser - 08-24-2006
I think it is A (late onset and mild)
0 - ArchivalUser - 08-24-2006
i was thinking that also, but it said deletion, not mutation
0 - ArchivalUser - 08-24-2006
agree with unocutie for b
duchenne = no dystrophin while in beckers we see just a bit
0 - ArchivalUser - 08-24-2006
B.
0 - ArchivalUser - 08-24-2006
guys...the answer is a........check out the age...14 yrs...tooo old for duchenne...in duchenne,symptoms appear by 5 yrs......you are right that in duchenne there is complete absence of dystrophin.....
0 - ArchivalUser - 08-24-2006
i see the age, but i just went with the deletion
0 - ArchivalUser - 08-24-2006
There is deletion in dystrophin gene in both...
0 - ArchivalUser - 08-24-2006
becker is a mutation