q4 - shawn3387 - Printable Version +- USMLE Forum - Largest USMLE Community (https://www.usmleforum.com) +-- Forum: USMLE Forum (https://www.usmleforum.com/forumdisplay.php?fid=1) +--- Forum: Step 1 (https://www.usmleforum.com/forumdisplay.php?fid=2) +--- Thread: q4 - shawn3387 (/showthread.php?tid=135868) |
q4 - shawn3387 - ArchivalUser - 11-05-2006 The fact that type IV osteogenesis imperfecta can be caused by defects on COLIA 1 and COLIA 2 is an example of a. Gonadal mosaicism b. Genetic heterogeneity c. Allelic heterogeneity d. Polymorphism 0 - ArchivalUser - 11-05-2006 b??? 0 - ArchivalUser - 11-05-2006 b??? 0 - ArchivalUser - 11-05-2006 c?? 0 - ArchivalUser - 11-05-2006 c?? 0 - ArchivalUser - 11-05-2006 The answer is b. Genetic heterogeneity is defined as a situation in which mutations of different genes produce similar or identical phenotypes. Gonadal mosaicism refers to mutation affecting some of the germ cells (sperm or eggs). Allelic heterogeneity refers to the state in which multiple alleles at a single locus can produce a disease phenotype or phenotypes. 0 - ArchivalUser - 11-05-2006 The answer is b. Genetic heterogeneity is defined as a situation in which mutations of different genes produce similar or identical phenotypes. Gonadal mosaicism refers to mutation affecting some of the germ cells (sperm or eggs). Allelic heterogeneity refers to the state in which multiple alleles at a single locus can produce a disease phenotype or phenotypes. 0 - ArchivalUser - 08-15-2008 ..... |