ulcer - recall - Printable Version +- USMLE Forum - Largest USMLE Community (https://www.usmleforum.com) +-- Forum: USMLE Forum (https://www.usmleforum.com/forumdisplay.php?fid=1) +--- Forum: Step 2 CK (https://www.usmleforum.com/forumdisplay.php?fid=3) +--- Thread: ulcer - recall (/showthread.php?tid=178773) Pages:
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ulcer - recall - ArchivalUser - 04-14-2007 you have a 34 year old patient who has had a motor vehicle accident and is in the ICU with multiple fractures...etc.... the patient is unconsious and on a ventilator.......what is the preferred medication fro the prevention of stress ulcers in this setting: 1...Cimitidine 2....omeprazole 3...sacralfate 4...misoprostol 5 antacid 0 - ArchivalUser - 04-14-2007 5. 0 - ArchivalUser - 04-14-2007 in there any I/v form of antacid ? 0 - ArchivalUser - 04-14-2007 3.. 0 - ArchivalUser - 04-15-2007 should be 222222... 0 - ArchivalUser - 04-15-2007 4? 0 - ArchivalUser - 04-15-2007 Based on this ......... Probably 3 3 http://www.brighamandwomens.org/pharmacoepid/Research/EduMaterials/Acid%20suppression%20update%20July%202002.pdf One large meta-analysis found that sucralfate (1 gm q.i.d.) is as effective as H2 blockers or PPIs in these critically ill patients. A more recent randomized controlled trial showed decreased incidence of GI bleeding with i.v. ranitidine compared to sucralfate, but no difference in mortality. Some studies suggest that nosocomial pneumonia may occur less often with use of sucralfate in ventilated patients as compared to H2 blockers (ranitidine 50 mg i.v. t.i.d.). Intravenous PPIs have not been studied for efficacy in stress ulcer prophylaxis. Their use may be appropriate in the very limited number of patients who cannot be given sucralfate or an i.v. H2 blocker. 0 - ArchivalUser - 04-15-2007 but this patient is unconsious..... how can you give sucralfate PO? 888888 - ArchivalUser - 04-15-2007 can gve thru NG BUT STILL its far more convenient to gvei/v h2 blockers as ventilato ris mentioned so i ll go for 3 as well 0 - ArchivalUser - 04-15-2007 sorry i didnt think about the NG Thank you |