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A 48-year-old man - rehellohie - Printable Version

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A 48-year-old man - rehellohie - ArchivalUser - 09-09-2007

A 48-year-old man is evaluated for progressive exertional dyspnea and nonproductive cough. He is an ex-smoker (30-pack-years) and has gastroesophageal reflux, systemic hypertension, and hypothyroidism. His medications include a proton pump inhibitor, an ACE inhibitor, and thyroid hormone replacement.

On physical examination, sclerodactyly is noted and the P2 component of S2 is increased in intensity. Bibasilar, inspiratory crackles are audible. There is no peripheral edema. HRCT scan of the chest shows reticular lines most prominent in the periphery of the lower lobes, accompanied by patchy, ground-glass opacities. A patulous esophagus, enlarged pulmonary arteries, and mildly dilated right ventricle are noted. Pulmonary function testing shows a forced expiratory volume in 1 sec (FEV1) 84% of predicted, a forced vital capacity (FVC) 78% of predicted, and a diffusing lung capacity for carbon monoxide (DLCO) 39% of predicted. Pulse oximetry with the patient at rest and breathing room air is 94%; with brisk walking, the oximeter only intermittently obtains a signal. Rheumatoid factor is negative. Antinuclear antibody titer is 1:160 (one dilution above the upper limit of normal).

Which of the following is the most likely diagnosis?

A Idiopathic pulmonary fibrosis
B Systemic lupus erythematosus with pulmonary involvement
C Hypersensitivity pneumonitis
D Cranial nerve dysfunction
E Scleroderma with lung involvement






0 - ArchivalUser - 09-09-2007

B.


0 - ArchivalUser - 09-09-2007

E Scleroderma with lung involvement


0 - ArchivalUser - 09-09-2007

* Lung disease is the most common cause of morbidity and mortality in systemic sclerosis.
* In scleroderma, both interstitial lung disease and pulmonary hypertension can develop (both independently or together) and have an adverse effect on outcome.
* Pulmonary disease can be the initial clinical manifestation of scleroderma.


0 - ArchivalUser - 09-09-2007

eeeee


0 - ArchivalUser - 09-10-2007

could please explain me about ventilator settings
thanks


0 - ArchivalUser - 09-10-2007

EE