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+--- Thread: can someone please explain!!! - coolzone (/showthread.php?tid=268630)
can someone please explain!!! - coolzone - ArchivalUser - 02-07-2008
Testicular cancer and ovarian idetification on the basis of tumor markers
1. Seminoma : the most common type : LDH
2. Non seminomas : choriocarcinoma : b-Hcg
3. ????
please someone help me with this ..
0 - ArchivalUser - 02-07-2008
for seminoma Idont know why!
but for choriocarsinoma,because it is originally from synsisiotrophoblast,and chorion
0 - ArchivalUser - 02-07-2008
i just want to know the specific tumor markers for the diff cancer types ..
the ones which are specific ..
please
0 - ArchivalUser - 02-07-2008
seminoma-PLAP
choriocarcinoma-hcg
leydig cell-estrogen
teratoma-hcg/afp
endodermal sinus tumor-afp
0 - ArchivalUser - 02-07-2008
3. Embryonal carcinoma: b-hcg/AFP
4. Yolksac carcinoma: AFP
5. Teratoma: none
0 - ArchivalUser - 02-07-2008
TESTICULAR GERM CELL TUMORS:
*Seminoma=placental alkaline phosphatse
*Embryonal Ca=(non specific)AFP,B-hCG
*Chorioca=B-hCG
*Yolk sac tumors=AFP(and remeber schiller duvall bodies)
~AFP(alpha fetoprot)is never elevated in seminoma.
~LDH may be elevated in either type.
~Liver function elevated in presence of mets.
~Anemia on advanced cases.
0 - ArchivalUser - 02-07-2008
great info guys ..thanks