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+--- Thread: Conceptual Q ------------- Pharma 2 - irfanmir (/showthread.php?tid=304256)
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Conceptual Q ------------- Pharma 2 - irfanmir - ArchivalUser - 05-22-2008
49 yrs old alcoholic is diagnosed with breast cancer. his antioncotic regiemn include two drug therapy since the cancer is in initial stages. which of the folowing of his regiemn most likely to cause cardiotoxicity.
A Paclataxil
B Tamoxifen
C Doxorubicin
D Cyclophosphmide
E Trastuzumab
0 - ArchivalUser - 05-22-2008
the subject is male guys
0 - ArchivalUser - 05-22-2008
eee......simple
0 - ArchivalUser - 05-22-2008
why not C?
0 - ArchivalUser - 05-22-2008
100 % CCCCCCCCCCCCCCCC
0 - ArchivalUser - 05-22-2008
Trastuzumab (Herceptin)
Mechanism Monoclonal antibody against HER-2 (erb-B2). Helps kill breast cancer cells that
overexpress HER-2, possibly through antibody-dependent cytotoxicity.
Clinical use Metastatic breast cancer.
Toxicity Cardiotoxicity. FA
0 - ArchivalUser - 05-22-2008
Special attention must be given to the cardiotoxicity induced by doxorubicin. Irreversible myocardial toxicity, manifested in its most severe form by life-threatening or fatal congestive heart failure, may occur either during therapy or months to years after termination of therapy.
0 - ArchivalUser - 05-22-2008
nt c..coz doxo nt used in breast cancer...
0 - ArchivalUser - 05-22-2008
so C
0 - ArchivalUser - 05-22-2008
i like when u guys talk abt Q well those who answer C are right. because the cancer is in initial stage. Good guys trastuzumab is for metastatic cnacer.