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+--- Thread: Diabetic patient on diet control.... - sunshine09 (/showthread.php?tid=306775)
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Diabetic patient on diet control.... - sunshine09 - ArchivalUser - 05-31-2008
A 47-yr old obese manis being evaluated for 3 month h/o wt gain and fatigue.3+glucouria in initial lab screeing. 2-hr postparandial glucose level 260 mg/dl.initial therapy is diet control,exercise,and close monitoring of glucose,lipid and BP.which of the following would be a consequence of his metabolic state at the time of initial presentation ?
a.activation of pyruvate dehydrogenase,
b.deactivation of fatty acid synthase,
c.deactivation of citrate shuttle,
d.decrese level of acetyl coA,
e.increased conversion of tryglyceride to glycerol
0 - ArchivalUser - 05-31-2008
I am right on this one, will read more about physiopath
Thanks .
0 - ArchivalUser - 05-31-2008
ccccccc
0 - ArchivalUser - 05-31-2008
seriously, it is type2 DM but what could be the answer, this is a good qs
0 - ArchivalUser - 05-31-2008
it is a good one. insulin activates fatty acid synthase, and lipolysis is increased in DM.
maybe it's eee?
0 - ArchivalUser - 05-31-2008
jazzblue if insulin activates fatty acid synthase, and lipolysis is increased in DM.
Isn't TGs synthesis and storage, answer E? but u sad lipolysis in DM
0 - ArchivalUser - 05-31-2008
hey jazz..if lipolysis activated..then person shud loose wt na...
i think its insulin resistance..n hence cellular def of insulin..so citrate shuttle hampered...wat say jazz n okt3
0 - ArchivalUser - 05-31-2008
metabolism always confuses me
harsh, the citrate shuttle and FA synthase r in the same pathway of FA synthesis, what about bbb?
0 - ArchivalUser - 05-31-2008
D?
0 - ArchivalUser - 05-31-2008
yep...jazz...if jus decrese in insulin is wat we r assuming...then B C D E all r rite....m totally confused nw..