q4 - ebnalfady - Printable Version +- USMLE Forum - Largest USMLE Community (https://www.usmleforum.com) +-- Forum: USMLE Forum (https://www.usmleforum.com/forumdisplay.php?fid=1) +--- Forum: Step 1 (https://www.usmleforum.com/forumdisplay.php?fid=2) +--- Thread: q4 - ebnalfady (/showthread.php?tid=330912) |
q4 - ebnalfady - ArchivalUser - 08-24-2008 A 50-year-old man presents with renal colic and an intravenous pyelogram demonstrates "clumps" of contrast medium limited to the medulla. Multiple small stones are also seen. Blood chemistries are all within normal limits. What is the most likely explanation for these findings? A. Adult polycystic renal disease B. Horseshoe kidney C. Infantile polycystic renal disease D. Medullary sponge kidney E. Renal dysplasia 0 - ArchivalUser - 08-24-2008 dd? 0 - ArchivalUser - 08-24-2008 try before posting the answer 0 - ArchivalUser - 08-24-2008 Ans is D Olga posted corr ans 0 - ArchivalUser - 08-24-2008 SOVIET UNION (PREVIOUS NAME) IS SUPER TODAYYYYYYYYY Explanation: The correct answer is D. This is a classic presentation for medullary sponge kidney, which has a male predominance and typically presents at 40-60 years of age. Histologically, medullary sponge kidney shows multiple small cysts lined by columnar or cuboidal epithelium localized to the medullary collecting tubules. The cysts can contain laminated concretions of calcium phosphates. Renal failure is rare in patients with medullary sponge kidney and the pathogenesis for the lesion has not been clarified. The rare uremic medullary sponge kidney is distinguished from the more common form by occurrence in 20-30 year-olds, salt-losing nephropathy, and progression to renal failure. The kidney of adult polycystic disease (choice A) is massively enlarged and filled throughout with round cysts of varying sizes. Adult polycystic kidney disease often presents with hypertension rather than renal failure or stones. Horseshoe kidney (choice B) involves fusion of the upper or lower (most common) pole of the kidney. It is fairly common (as high as 1:500), and is typically an incidental finding at autopsy. Infantile polycystic kidney (choice C) produces a small kidney with round medullary cysts and "radiating" linear cortical cysts. Renal dysplasia (choice E) can also cause cystic change in a kidney, but typically involves only the medulla and cortex of part of the kidney. |