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+--- Thread: hepatitis B virus - okt3 (/showthread.php?tid=374185)
hepatitis B virus - okt3 - ArchivalUser - 01-02-2009
A clinical study of hepatitis B infection is conducted. It is observed that when hepatocytes become infected by hepatitis B virus, macrophages that encounter this hepatocyte are activated. Which of the following substances elaborated by this macrophage is most likely to result in subsequent activation of NK cells?
A Interferon gamma
B Interleukin-12
C Nitric acid
D Phagocyte oxidase
E Tumor necrosis factor
0 - ArchivalUser - 01-02-2009
IL-12
0 - ArchivalUser - 01-02-2009
CORRECT. IL-12 is particularly helpful in stimulating NK cells to destroy the virally infected cell.
0 - ArchivalUser - 01-03-2009
ok ...how bout ..substance which ll inhibit NK CELL???
WHICH MOLECULE INHIBIT NK CELL???
0 - ArchivalUser - 01-03-2009
why cant it be A OR E which will stimulate nk cells, its given in kaplan immunolgy page 384, diagram representation, TH 1 --INF GAMMA----CD8, NKCELLS. CAN U GUYS CLARIFY MY DOUBT? WHY IS IT ONLY IL 12 STIMULATING NK?
0 - ArchivalUser - 01-03-2009
just look into NUTSHELL on page 382.