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+--- Thread: how zinc helps in wilsons dz - jmd (/showthread.php?tid=46839)
how zinc helps in wilsons dz - jmd - ArchivalUser - 06-04-2005
do u know.thanx.
0 - ArchivalUser - 06-04-2005
red. cu absorp.
0 - ArchivalUser - 06-04-2005
zinc increases excretion of cu
0 - ArchivalUser - 06-04-2005
zn stimulate synth. of metallothionine in Gi mucosa and red. absop.
0 - ArchivalUser - 06-04-2005
ORAL ZINC ACETATE ,50 MG THREE TIMES DAILY PROMOTES FECAL CU EXCRETION& MAY BE USED IN MANTAINANCE THERAPY AFTER DECOPPERING WITH A CHELATING AGENT OR AS A FIRST LINE THERAPY IN PRESYMPTOMATIC OR PREGNANT PT.
---ref. CMDT
0 - ArchivalUser - 06-05-2005
ahahah ok ok,,
Well Zn reduces the bioavailability of cu.,, it's not that it sucks from blood and thows in to the stool,,
Zn doesn't bind with copper,, zn stimulate the synthesis of the metal0... protein in the lining of the gut,, that in turn binds with the dietry cu,, before it could enter in to the blood,, and as the mucosa sheds,, it goes out with the stool,, simply reduces the bioavailability.,, CMDT gives sweet but incomplete.