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+--- Thread: NBME 5 ans plz... - arpddvd4u (/showthread.php?tid=525121)
NBME 5 ans plz... - arpddvd4u - ArchivalUser - 08-12-2010
A biosynthetic error in reading the genetic code gives rise to an enzyme that folds in an abnormal manner.Which of the following is most likely to happen to this enzyme?
a denaturation and refolding
b faster degradation
c inactivation by phosphorylation
d tansportation out of the cell via the golgi complex
A 66year old man who is undergoing chemotherapy for lekumia has a 3 day history of progressive fever,headache,nausea, and deteoration of mental acuity.analysis of csf shows lymphocytic pleocytosis,a normal glu conc. , and a slightly increased protein conc..The causual agent is presumptively identified by a positive Indian ink test and later confirmed with culture Which of the following is the major virulence factor of the infecting organism producing this disease?
a antigenic variation
b exotoxin
c Ig protease
d leuckocidin
e polysaccharide capsule
9 - ArchivalUser - 08-12-2010
E.polysaccharide capsule ..
0 - ArchivalUser - 08-12-2010
09usmle ,
acc to ques lymphocytic pleocytosis,a normal glu conc. , and a slightly increased protein conc.. goes in favour of viral or fungal etiology but not bacterial .. and =ve indian ink test,m thinking of cryptococcous ???
key says E. but im doubtful so could u explain why E???
0 - ArchivalUser - 08-12-2010
Q1 B ( ubiquitin mediated degradation )
Q2- E
9 - ArchivalUser - 08-13-2010
hi arpddvd4u,
you are thinking absolutely right .
this is cryptococus..that has thick poltsacharide capsule .