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About Kawasaki's Disease - verysmartgirl - ArchivalUser - 08-20-2005

Can someone help me by giving some "key points" about clinica of kawasaki disease!!! i Always miss this disease no matter many times i read,i couldn't find out key points........i diagnose it as a Viral disease........please someone!!!
Thanx


0 - ArchivalUser - 08-20-2005

KAWASAKI`S DISEASE(mucocutaneous L.N.syn.):commom in <4yrs,Japan,s/s:fever,conjunctivitis,erosion of oral mucosa,maculopapular rash,lymphadenopathy,affects arteries(segmental necrotising vasculitis),common in coronary art.,aneurysm formation.
Main point is----MI in children.

Hope it helps.GL.


0 - ArchivalUser - 08-20-2005

that a great answer Savi , inaddition , it is the only disease in children whereby Aspirin 80-100mg qid is given that wouldn't cause Reye syndrome , intravenous immunoglobulin is also given as a drug of choice


0 - ArchivalUser - 08-20-2005

ebony,
Are you sure that aspirin will not cause Rye syndrome in Kawasaki or just because the risk is worth taking? Do you have any reference for this point?


0 - ArchivalUser - 08-20-2005

Thanx Savy and ebony.But i was confused B'coz fever conjuctivitis,erosion of aral mucosa( due to dehydration and high fever can be seen in any child),L/adenopathy can be seen in any disease.....lets say Measles also.........or SSSS also,scarlet also and toxic shock syndrome also..........am i right?Can u clear something furthur for me please.
Ebony: as far as i know Reye with aspirin is not just due to aspirin use in cdildren, it is if in Viral infection u use aspirin causes Reye's, and Kawasaki's is not a Viral illness.



0 - ArchivalUser - 08-20-2005

HI VSG,
LOOK OUT FOR THESE BUZZWORDS: RED PALMS(i USUALLY LOOK 4 THIS)+ 1 LN >1.5CM(U/L)+FEVER(>5 DAYS)+CRACKED LIPS&STRAWBERRY TONGUE(ANOTHER INDICATOR)+EDEMA OF HANDS AND FEETS(ANOTHER UNIQUE FEATURE)

Nonspecific=b/l non purulent conjunctivitis+injected pharynx+PERIUNGAL DESQUAMATION+truncal polymorphous rash

Labs:thrombocytosis+anemia
Always do ECHO


0 - ArchivalUser - 08-20-2005

verysmartgirl,
actually,i`m preparing for step1 and q on kawasaki`s comes commonly as:child with MI,sometime they mention country i.e.Japan etc.I don`t know about step2.
But i can say that,presentation is diff.in diff.diseases you mentioned.e.g.in case of meseales,rash&koplik`s spots are diff.than erosion of oral mucosa&rash of kawasaki;fever and other toxic sym.in TSS is diff.(more severe) than just feverish in kawasaki;no lymphadenopathy in TSS or measles.Mainly,child with coronary art.symptoms--is imp.than other coexisting signs&symptoms.
Hope you got my point.


0 - ArchivalUser - 08-20-2005

Thanx alot Savi........And Good Luck



0 - ArchivalUser - 08-20-2005

mucocutaneous lesion+vasculities(coronary artey-making it the cause of MI in children)
dd-scarlet fever


0 - ArchivalUser - 08-20-2005

To Dwnchao pls consult Harrison's principle of medicine 16th edition, 5 minute clinical consult and Ferri diseases 2005