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treatment confusion - akm07 - ArchivalUser - 09-19-2010

how do we treat cold IgM hemolysis problem ( steroid-->splenectomy--> cyclophosphamide??)

and how we manage waldenstrom's hyperviscosity from high IgM (plasmapheresis?)

little confused pls put some input


0 - ArchivalUser - 09-19-2010

wald. is tx with plasmapheresis, and then u tx the underlying lymphoma.


0 - ArchivalUser - 09-19-2010

igm hemoly. is tx with steroids


0 - ArchivalUser - 09-19-2010

Mx of IgM hemolysis:
first avoid cold...............If fails, cyclosporine/cyclophosphamide/azathioprne
Can use Rituximab

steroid n splenectomy - as distruction is in liver..... never use in IgM ds


0 - ArchivalUser - 09-19-2010

not sure about waldenstrom's hyperviscosity Mx