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+--- Thread: Ist thought drug - drforget (/showthread.php?tid=669545)
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Ist thought drug - drforget - ArchivalUser - 04-05-2012
patient, with blurred vision, returned from Africa, seeing halos around lights at night, has itching while showering, O/E: the is corneal deposits, and bilateral diminished in visual acuity and retinal edema, lab shows leukopenia, normal CXR
what drug cause the findings with mechanism of action???
0 - ArchivalUser - 04-05-2012
bro spare us some brain cells....
give us some options lol this is a difficult question!
0 - ArchivalUser - 04-05-2012
okay:
a Digoxin
b cephalosporin
c chloroquine
d steroids
e alcohol
0 - ArchivalUser - 04-05-2012
He must've have been given Chloroquine in Africa. This is toxic becuase it breaks hemoglobin and separates out heme inside the parasite-ridden cell. this heme breaks into Fe- Protoporphrin IX ( FP ) . This forms a complex with chloroquine FP-chloroquine, which is highly toxic to cells and autodigests it..Nice question.
0 - ArchivalUser - 04-05-2012
The parasite breaks down hemobglobin is what I mean,that forms the complex later with CQ
0 - ArchivalUser - 04-05-2012
yah im gonna go with
C: chloroquine or could be A digioxin too
0 - ArchivalUser - 04-05-2012
answer is chloroquine toxicity which is responsible for the above findings:
))))
0 - ArchivalUser - 04-05-2012
thank you and i pray that u never write a single question for step thanks
0 - ArchivalUser - 04-05-2012
no digoxin is not associated with leukopenia or normal CXR, patient with Heart failure treated with Digoxin will not going to have normal CXR.
0 - ArchivalUser - 04-05-2012
oh true true ... thank you