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+--- Thread: >??????????????????????????????????? - zen786 (/showthread.php?tid=678100)
>??????????????????????????????????? - zen786 - ArchivalUser - 05-21-2012
Failure of a Na+/K+ ATPase pump .... will that lead to cellular edema or not ?
0 - ArchivalUser - 05-21-2012
zen u are cheating in my question pal
0 - ArchivalUser - 05-21-2012
of course....it is the earliest step in Hypoxic cell injury, when ATP depletion causes Na/K ATPase pump dysfunction, Na accumulates in the cell, leading to cell swelling.
0 - ArchivalUser - 05-21-2012
no no im not cardio .... im reading this in pathoma right now as we speak .... so i just wanted to confirm something sorry ....
im trying to figure out the correlation of ATP*** itself with edema.... so decrease ATP --> decrease Na/K ---> shouldn't lead to edema...
0 - ArchivalUser - 05-21-2012
any hypoxic injury to a cell will lead to cellualr swelling
0 - ArchivalUser - 05-21-2012
NVM yes wikidr you are right... decrease ATP ==> increase sodium intracellular ==> edema [cellular swelling]
0 - ArchivalUser - 05-21-2012
Na/K ATP ase pump needs ATP in order to function properly, as its name says. if you do not hv ATP, then-----> dec. Na/K atpase activity ------> Na stays inside the cell/ accumulates --------> cellular swelling
0 - ArchivalUser - 05-21-2012
yup thank you herniation and wikidr
godbless you guys!!
0 - ArchivalUser - 05-21-2012
ofcourse lead to edema and cell lysis..........