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a question - - ArchivalUser - 06-04-2003
usch
Can anyone explain the direct relationship between citrate and phosphfructokinase?
0 - ArchivalUser - 06-05-2003
niti
PFK is inhibited by citrate & ATP
0 - ArchivalUser - 06-05-2003
usch
How are they linked, by what pathway?
0 - ArchivalUser - 06-05-2003
niti
PFK is a rate limiting enzyme in glycolysis; accumulation of citrate which is one of the products of the krebs cycle inhibits glycolysis & citrate enters in the krebs cycle this happens in the aerobic conditions.