10-07-2006, 08:51 AM
A 56-year-old Caucasian male is admitted for cellulitis of the foot. He was started on IV nafcillin. He has a history of diabetes, type 2, and he takes metformin and glipizide. Two days later, he developed a petechial rash all over the body, and begins complaining of joint pains. His lab results are:
Hb
11 g/dL
WBC
13,000/cmm with 10% eosinophils
BUN
40 mg/dL
S.Creatinine
2.1 mg/dL
Urine Hansel stain is positive. Which of the following is the most likely pathology involved in this patient™s renal failure?
A. Immune-complex deposition
B. Type 1 hypersensitivity reaction
C. Type 4 hypersensitivity reaction
D. Acute tubular necrosis
Hb
11 g/dL
WBC
13,000/cmm with 10% eosinophils
BUN
40 mg/dL
S.Creatinine
2.1 mg/dL
Urine Hansel stain is positive. Which of the following is the most likely pathology involved in this patient™s renal failure?
A. Immune-complex deposition
B. Type 1 hypersensitivity reaction
C. Type 4 hypersensitivity reaction
D. Acute tubular necrosis