10-09-2006, 06:29 AM
plz some1 explain me the basics of its relation with extra/intravascular hemolysis.
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LDH n RC? - wish
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10-09-2006, 06:55 AM
haptoglobulin is dec in intravascular hemolysis ex PNH......ldh is inc in most hemolytic anemia..sorry not being specific
10-09-2006, 11:16 AM
haptoglobulin is actually Hb binding protein in intravascular hemolysis it is dec. d/t carrying away Hb.
Ldh is enzyme inside RBCs converting pyruvate to lactate.so hemolysis releases it .
10-09-2006, 03:18 PM
intravascular hemolysis is always fulminant with shock, hematuria, hemoglobunuria etc, more and there is mostly a precipitating factor, drugs, autoantibodies, infections etc. so also look for this clues in the q stem
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