hiv - saonew

[ArchivalUser]

The gag gene in the HIV viral genome encodes structural proteins that protect the viral chromosome, but only after they undergo post-translational activation. Which of the following most closely represents a similar type of post-translational activation to that of the gag structural protein?

A. conversion of proinsulin to insulin

B. prenylation of a membrane protein

C. phosphorylation of tyrosine residues

D. formation of disulfide bonds in a-keratin

E. attachment of a prosthetic group

[ArchivalUser]

a...

hello.. hows everyone doin

[ArchivalUser]

This a hard one..

A..

[ArchivalUser]

we thought you left..

[ArchivalUser]

yea i did..was eating breakfast

[ArchivalUser]

since it says post translational activation A?

[ArchivalUser]

one both involve proteeolysis to become active

[ArchivalUser]

Correct: A. The gag structural protein undergoes proteolytic cleavage during its activation similar to the proteolytic conversion of proinsulin to insulin. This process is the target of anti-HIV drugs called protease inhibitors