Drug induced hepatic...... - leschnyhan

[ArchivalUser]

Which of the following antibiotics is most likely to cause cholestasis?
A.A Co-amoxiclavi
B.A Gentamicin
C.A Ciprofloxacin
D.A Trimethoprim
E.A Ceftazidimei

[ArchivalUser]

ciprofloxacin

[ArchivalUser]

amoxicillin-clavulanic acid?

[ArchivalUser]

inflamatory type cholestasis: amoxicillin-clavulanic acid, Erithromycin, thiazides

[ArchivalUser]

Augmentin is the right answer

[ArchivalUser]

Good AAAA is correct.

Drug-induced liver disease ------> hepatocellular, cholestatic or mixed


*Hepatocellular

paracetamol

sodium valproate, phenytoin

MAOIs

halothane

anti-tuberculosis: isoniazid, rifampicin, pyrazinamide

statins, fibrates

alcohol

amiodarone

methyldopahe

*The following drugs tend to cause cholestasis (+/- hepatitis):

oral contraceptive pill

antibiotics: flucloxacillin, co-amoxiclav, erythromycin, nitrofurantoin

anabolic steroids, testosterones

phenothiazines: chlorpromazine, prochlorperazine

sulphonylureas

rare reported causes: nifedipine