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Lineweaver-Burk plot - saonew

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Lineweaver-Burk plot - saonew
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#1
04-01-2007, 10:18 PM
Which of the following will be unchanged in a Lineweaver-Burk plot of an enzyme with and without a competitive
inhibitor?


A. Km

B. Slope

C. x-intercept

D. y-intercept
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#2
04-01-2007, 10:20 PM
D. y-intercept
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#3
04-01-2007, 10:24 PM
ddd
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#4
04-01-2007, 10:26 PM
YES D)
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#5
04-02-2007, 12:04 AM
Can anyone explain te answer?]
thx
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#6
04-02-2007, 12:26 AM
competitive inhibitors resemble the substrate and compete for binging to the active site of the enzyme. They increase Km, but have no effect on Vmax. So in Lineweaver-Burk plot, the Y-intercept which stands for 1/Vmax keeps unchanged.
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