Acute graft rejection - dramsinhere

[ArchivalUser]

hyperacute--- type 2 -- bcoz of preformed antibodies -- compare it with Abo incompatibility...ACUTE is TYPE 4 .. INVOLVING T CELLS

[ArchivalUser]

acute graft rejection has 2 subtypes one of them is type 4 while the other is type 2. see goljan rapid review. and hyperacute is type 2.

[ArchivalUser]

I think I should share what I discovered doing Q about post LIVER transplantation .
1. I sow if they want the answer to be ACUTE rejection the case give you an info just with biopsy -= Vasculitis of the GRAFT,

2. If they want answer to be Acute GRAFT versus host DISEASE- they do the Q like that : symptoms from the graft and GI symptoms + systemic symptoms


3. If it is a Chronic GVH - they describe a fibrosis in the graft

[ArchivalUser]

type 4

[ArchivalUser]

type 4

[ArchivalUser]

ok agrre type 4 as i ve memorised it
but
can any1 explain

traditionally it take 72 hrs for type4 then how come it be 24 in acute

[ArchivalUser]

Defination of acute rejection:

This may occur in DAYS of transplantation in untreated recipient .2 types
1.Acute cellular: with invlvement of mononuclear cel infiltration,and has both CD4 and CD8 lymphos
2.Acute humoral:antibody mediated vasculitis

Hyper acute:
within mts or hours .also Ag-Ab reac at the level of vascular endo.

So acute cellular is type 4

[ArchivalUser]

genius can u elobrate dint understand why every1 is saying its type 4 . thnx

[ArchivalUser]

keira involvement of mononuclear cells +lymphos make it type 4