aztreonam -

[ArchivalUser]

usmle_step1

Aztreonam inhibits cell wall synthesis, but it's not active against gram + organisms. Why is that? Isn't it counter-intuitive?

Thanks,
Jane

[ArchivalUser]

ali

because it only attach to transpeptidase of gram -ve not positive , so only inhibit cell wall synthesis in gram -ve

[ArchivalUser]

kany

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thanks
kany